Unzipped and loaded
نویسنده
چکیده
It is well known that the products of chromosome replication are paired to ensure that the sisters segregate away from each other during mitosis. A key issue is how cells pair sister chromatids but preclude the catastrophic pairing of nonsister chromatids. The identification of both replication factor C and DNA helicases as critical for sister chromatid pairing has brought new insights into this fundamental process.
منابع مشابه
Unzipped and loaded: the role of DNA helicases and RFC clamp-loading complexes in sister chromatid cohesion
It is well known that the products of chromosome replication are paired to ensure that the sisters segregate away from each other during mitosis. A key issue is how cells pair sister chromatids but preclude the catastrophic pairing of nonsister chromatids. The identification of both replication factor C and DNA helicases as critical for sister chromatid pairing has brought new insights into thi...
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عنوان ژورنال:
- The Journal of Cell Biology
دوره 169 شماره
صفحات -
تاریخ انتشار 2005